Stable salts of S-adenosyl-L-methionine with polyanions

Details Stable salts of S-adenosyl-L-methionine with polyanions Stable salts of S-adenosyl-L-methionine with polyanions

1985-08-09

1988-08-16

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, 536 27, A61K 3170, C07H 19167

Patent

active

047646039

ABSTRACT:
Stable salts of S-adenosyl-L-methionine with water-soluble polyanions, such as polyphosphates, polyvinylsulfonates -sulfates or -phosphates, polyacrylates, polystyrene sulfonates, are described.
The salts according to the invention, prepared by precipitation from aqueous solutions of pH not exceeding 3.5, possess peculiar stability, solubility, nonhygroscopicity and are valuable for use as active constituents in pharmaceutical compositions.

REFERENCES:
Allan et al., Can. J. Microbiol., 26, pp. 912-920, 1980.
Miller, Can. J. Microbiol., 30, pp. 236-246, 1984 (Feb.).
Aldrich Catalog Handbook of Fine Chemicals, 1984, Aldrich Chem. Co., Milwaukee, Wis., pp. 1400-1401.
March, Advanced Organic Chemistry, McGraw-Hill, New York, 1968, p. 489.

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