Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-04-18
2011-12-06
Kosson, Rosanne (Department: 1652)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S069100, C435S227000, C514S001400
Reexamination Certificate
active
08071741
ABSTRACT:
A mutein recombinant adenosine deaminase having any oxidizable cysteine residue replaced by a non-oxidizable amino acid residue is disclosed. Stabilized recombinant adenosine deaminase, polymer conjugates and methods of treatment using the same are also disclosed.
REFERENCES:
patent: 5122614 (1992-06-01), Zalipsky
patent: 5324844 (1994-06-01), Zalipsky
patent: 5346823 (1994-09-01), Estell et al.
patent: 5349001 (1994-09-01), Greenwald et al.
patent: 5405877 (1995-04-01), Greenwald et al.
patent: 5567422 (1996-10-01), Greenwald
patent: 5612460 (1997-03-01), Zalipsky
patent: 5643575 (1997-07-01), Martinez et al.
patent: 5650234 (1997-07-01), Dolence et al.
patent: 5681567 (1997-10-01), Martinez et al.
patent: 5728560 (1998-03-01), Shorr et al.
patent: 5756593 (1998-05-01), Martinez et al.
patent: 5808096 (1998-09-01), Zalipsky
patent: 5849549 (1998-12-01), Barnett et al.
patent: 5919455 (1999-07-01), Greenwald et al.
patent: 5965119 (1999-10-01), Greenwald et al.
patent: 6113906 (2000-09-01), Greenwald et al.
patent: 6153655 (2000-11-01), Martinez et al.
patent: 6180095 (2001-01-01), Greenwald et al.
patent: 6207876 (2001-03-01), Kellems et al.
patent: 6251382 (2001-06-01), Greenwald et al.
patent: 6303569 (2001-10-01), Greenwald et al.
patent: 6366860 (2002-04-01), Rozzell, Jr. et al.
patent: 6395266 (2002-05-01), Martinez et al.
patent: 6556506 (2003-04-01), Naven
patent: 6624142 (2003-09-01), Zhao et al.
patent: 6638499 (2003-10-01), Martinez et al.
patent: 6703381 (2004-03-01), Ekwuribe et al.
patent: 6720306 (2004-04-01), Greenwald et al.
patent: 6824766 (2004-11-01), Greenwald et al.
patent: 6828401 (2004-12-01), Nho et al.
patent: 7053150 (2006-05-01), Kozlowski et al.
patent: 7087229 (2006-08-01), Zhao et al.
patent: 7122189 (2006-10-01), Zhao et al.
patent: 7413738 (2008-08-01), Zhao et al.
patent: 2003/0215436 (2003-11-01), Walsh et al.
patent: 2004/0136952 (2004-07-01), Bhaskaran et al.
patent: 2005/0220799 (2005-10-01), Sitkovsky et al.
patent: 2006/0286065 (2006-12-01), Zhao et al.
patent: 2007/0078219 (2007-04-01), Zhao et al.
patent: 2007/0166276 (2007-07-01), Zhao et al.
patent: 2007/0173615 (2007-07-01), Zhao et al.
patent: 2008/0159964 (2008-07-01), Blackburn et al.
patent: 2008/0249260 (2008-10-01), Zhao et al.
patent: WO 2007/149686 (2007-12-01), None
patent: WO 2008/034119 (2008-03-01), None
patent: WO 2008/034124 (2008-03-01), None
Alignment of instant SEQ ID No. 2 with SEQ ID No. 6 of Blackburn et al., US 2008/0159964 A1, NCBI Blast 2 web site, http://blast.ncbi.nlm.nih.gov/Blast.cgi, performed on Mar. 23, 2010.
Result 1, Geneseq protein database search, alignment of instant SEQ ID No. 1 with SEQ ID No. 5 of Blackburn et al., US 2008/0159964 A1, performed on Mar. 18, 2010.
GenBank/NCBI, conserved domain search for instant SEQ IQ No. 1, NCBI Blast website, http://blast.ncbi.nlm.nih.gov/Blast.cgi, performed on Jul. 9, 2010.
International Search Report and Written Opinion issued in PCT/US08160805 and dated Aug. 19, 2008.
Bota, et al. Purification of human adenosine deaminase for the preparation of a reference material. J Chromatogr B Biomed Sci Appl., 2000, vol. 737: 237-44, Abstract only.
Bhaumik et al. Mutational analysis of active site residues of human adenosine deaminase. J Biol Chem., 1993, 268: 5464-70.
Arredondo-Vega et al. Seven Novel Mutations in the Adenosine Deaminase (ADA) Gene in Patients with Severe and Delayed Onset Combined Immunodeficiency: G74C, V129M, G140E, R149W, Q199P, 462deIG and E337del. Hum Mutat., 1998, vol. 11: 482.
Lim et al. Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells. Proc Natl Acad Sci USA, 1989, vol. 86: 8892-6.
Onodera et al. Successful Peripheral T-Lymphocyte-Directed Gene Transfer for a Patient With Severe Combined Immune Deficiency Caused by Adenosine Deaminase Deficiency. Blood, 1998, 91:30-6.
U.S. Appl. No. 12/105,682 Entitled: Enzymatic Anticancer Therapy, US 2009/0047270 A1.
Kinoshita et al., 2005, Biochemistry, 44:10562-10569.
Liu et al., Nat. Methods, 2007 4(3):239-44.
Xie et al., Nat. Rev. Mol. Cell. Biol., 2006 7(10):775-82.
Ryu et al., Nat. Methods, 2006 3(4):263-65.
Deiters et al., Bioorg. Med. Chem. Lett., 2004 14(23):5743-5745.
Bogosian et al., J. Biol. Chem., 1989 264(1):531-539.
Tang et al., Biochemistry, 2002 41(34):10635-10645.
Budisa et al., Eur. J. Biochem., 1995 230(2):788-796.
Randhawa et al., Biochemistry, 1994 33(14):4352-4362.
Shearwater Corporation's 2001 catalog “Polyethylene Glycol and Derivatives for Biomedical Application”.
NOF Corp. Drug Delivery System catalog, Ver. 8, Apr. 2006.
Weihofen et al., J Biol Chem, 2004 279: 43330-43335.
Ludwig et al., BBRC, 2004 313:223-229.
Weihofen et al., J Biol Chem, 2005 14911-14917.
Blay et al, Cancer Res 1997, 57: 2602-2605.
Mujoomdar et al., Biochem Pharmacol 2003, 66: 1737-1747.
Spychala, Pharmacology & Therapeutics 2000, 87:161-173.
Adair, Am J Physiol Regul Integr Comp Physiol 2005, 289: R283-396.
Sitkovsky et al., Nat Rev Immunol 2005, 5:712-721.
Merighi et al., Neoplasia 2005, 7: 894-903.
Sideraki et al. Biochemistry, 1996 35:7862-7872.
Filpula David R.
Youngster Stephen K.
Defiante Farmaceutica, S.A.
Kosson Rosanne
Lucas & Mercanti LLP
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