Stable radioactive diagnostic agent and a non-radioactive carrie

Details Stable radioactive diagnostic agent and a non-radioactive carrie Stable radioactive diagnostic agent and a non-radioactive carrie

1982-12-02

1984-12-18

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, A61K 4300, A61K 4900

Patent

active

044890532

ABSTRACT:
A stable non-radioactive carrier for use in production of .sup.99m Tc-labeled radioactive diagnostic agent comprising a chelating agent, a water-soluble reducing agent for pertechnetate and a stabilizer chosen from ascorbic acid and erythorbic acid, and their pharmaceutically acceptable salts and esters in an amount of more than about 100 moles per 1 mol of said water-soluble reducing agent.

REFERENCES:
patent: 3981980 (1976-09-01), Baker et al.
patent: 4229427 (1980-10-01), Whitehouse
patent: 4232000 (1980-11-01), Fawzi
patent: 4233284 (1980-11-01), Fawzi
patent: 4247534 (1981-01-01), Bevan
Tofe et al., Chemical Abstracts, vol. 93, (1980), #128003r.
Tofe et al., Chemical Abstracts, vol. 85, (1976), #139239h.
Winchell et al., Chemical Abstracts, vol. 91, (1979), #153599f.
Tofe et al., Journal of Nuclear Medicine, vol. 17, No. 9, pp. 820-825, (1976).
Kirk-Othmer Encyclopedia of Chemical Technology, (2nd edition), p. 750, (1963).

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