Stable pre-occluded virus particle

Details Stable pre-occluded virus particle Stable pre-occluded virus particle

1994-08-25

1997-01-14

Guzo, David

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Virus or bacteriophage

424 932, 4352351, 4353201, 435 691, 435239, A01N 6300, C12N 701, C12N 702, C12P 2100

Patent

active

055936695

ABSTRACT:
A method of infecting insects is disclosed; the method utilizes a form of a baculovirus which is highly efficient at establishing infection and is normally destined to become occluded within the polyhedrin or granulin--Pre-occluded Virus (POV). Specifically, the POV as derived from a polyhedrin-minus or granulin-minus (lacking a functional polyhedrin or granulin gene) baculovirus is fed to insect larvae per os resulting in high infection rates. The stabilization and use of the POV form of polyhedrin-minus baculoviruses as an insecticide is also disclosed.

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