Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2008-09-02
2008-09-02
Eyler, Yvonne (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C544S366000, C544S295000, C514S254060, C514S253030
Reexamination Certificate
active
11546304
ABSTRACT:
The invention relates to the polymorph A of flibanserin, to a technical process for the preparation thereof, as well as to the use thereof for preparing medicaments.
REFERENCES:
patent: 3406178 (1968-10-01), Crocker et al.
patent: 3472854 (1969-10-01), Archer
patent: 4200641 (1980-04-01), Vandenberk et al.
patent: 4737500 (1988-04-01), Sorg
patent: 4792452 (1988-12-01), Howard et al.
patent: 4797399 (1989-01-01), Ueda et al.
patent: 4859692 (1989-08-01), Bernstein et al.
patent: 4886803 (1989-12-01), Sueda et al.
patent: 4940793 (1990-07-01), Botre et al.
patent: 4954503 (1990-09-01), Strupczewski et al.
patent: 4968508 (1990-11-01), Oren et al.
patent: 5002948 (1991-03-01), Perregaard et al.
patent: 5036088 (1991-07-01), Kitaura et al.
patent: 5225417 (1993-07-01), Dappen et al.
patent: 5405642 (1995-04-01), Gilis
patent: 5434156 (1995-07-01), Bjoerk et al.
patent: 5576318 (1996-11-01), Bietti et al.
patent: 5591743 (1997-01-01), Patoiseau et al.
patent: 5854290 (1998-12-01), Arnsten et al.
patent: 5883094 (1999-03-01), Fliri et al.
patent: 5977106 (1999-11-01), Patoiseau et al.
patent: 6083947 (2000-07-01), Granger et al.
patent: 6165513 (2000-12-01), Dansereau et al.
patent: 6281218 (2001-08-01), Cereda et al.
patent: 6284757 (2001-09-01), Sanner
patent: 6426087 (2002-07-01), Saslawski
patent: 6521623 (2003-02-01), Cereda et al.
patent: 6586435 (2003-07-01), Cereda et al.
patent: 6680071 (2004-01-01), Johnson et al.
patent: 7151103 (2006-12-01), Borsini et al.
patent: 7183410 (2007-02-01), Bombarda et al.
patent: 2003/0060475 (2003-03-01), Borsini
patent: 2003/0083228 (2003-05-01), Carpino et al.
patent: 2003/0119850 (2003-06-01), Bombarda et al.
patent: 2004/0023948 (2004-02-01), Green
patent: 2004/0048877 (2004-03-01), Friedl et al.
patent: 2004/0116532 (2004-06-01), Heacock et al.
patent: 2004/0147581 (2004-07-01), Taylor
patent: 2004/0180904 (2004-09-01), Beck
patent: 2004/0235861 (2004-11-01), Borsini
patent: 2005/0004105 (2005-01-01), Leahy et al.
patent: 2005/0037983 (2005-02-01), Dinan et al.
patent: 2005/0065158 (2005-03-01), Naylor et al.
patent: 2005/0159430 (2005-07-01), Bombarda et al.
patent: 2005/0239798 (2005-10-01), Pyke
patent: 2005/0245539 (2005-11-01), Mendla et al.
patent: 2006/0014757 (2006-01-01), Pyke
patent: 2006/0025420 (2006-02-01), Brauns et al.
patent: 2006/0052391 (2006-03-01), Dolsten
patent: 2006/0160822 (2006-07-01), Borsini
patent: 2006/0199805 (2006-09-01), Pyke et al.
patent: 2006/0204486 (2006-09-01), Pyke et al.
patent: 2006/0211685 (2006-09-01), Pyke et al.
patent: 2006/0252773 (2006-11-01), Ceci
patent: 2006/0258640 (2006-11-01), Ceci et al.
patent: 2006/0264511 (2006-11-01), Pyke
patent: 2006/0264512 (2006-11-01), Pyke
patent: 2007/0032654 (2007-02-01), Bombarda
patent: 2007/0072872 (2007-03-01), Borsini
patent: 2007/0105869 (2007-05-01), Pollentier et al.
patent: 2007/0123540 (2007-05-01), Ceci
patent: 2007/0196473 (2007-08-01), Friedl et al.
patent: 2008/0038346 (2008-02-01), Eisenreich et al.
patent: 2008/0038347 (2008-02-01), Eisenreich et al.
patent: 2008/0069873 (2008-03-01), Pearnchob et al.
patent: 904945 (1986-12-01), None
patent: 2455628 (2003-02-01), None
patent: 3620643 (1987-01-01), None
patent: 10138273 (2003-02-01), None
patent: 0200322 (1986-11-01), None
patent: 376607 (1990-04-01), None
patent: 497985 (1992-12-01), None
patent: 0 526 434 (1993-02-01), None
patent: 0526434 (1993-02-01), None
patent: 0705832 (1996-04-01), None
patent: 0816356 (1998-01-01), None
patent: 0982030 (2000-03-01), None
patent: 1256343 (2002-11-01), None
patent: 1285658 (2003-02-01), None
patent: 1518858 (2005-03-01), None
patent: 1674102 (2006-06-01), None
patent: 2023594 (1980-01-01), None
patent: 1992/1340 (1992-10-01), None
patent: H8-143476 (1996-06-01), None
patent: WO 92/03167 (1992-03-01), None
patent: WO 92/19606 (1992-11-01), None
patent: WO 93/03016 (1993-02-01), None
patent: WO 95/01965 (1995-01-01), None
patent: WO 95/34555 (1995-12-01), None
patent: WO 96/05834 (1996-02-01), None
patent: WO 96/16949 (1996-06-01), None
patent: WO 98/33784 (1998-08-01), None
patent: WO 98/42344 (1998-10-01), None
patent: WO 99/19302 (1999-04-01), None
patent: WO 00/28993 (2000-05-01), None
patent: WO 00/64441 (2000-11-01), None
patent: WO 01/12170 (2001-02-01), None
patent: WO 01/21593 (2001-03-01), None
patent: WO 02/24662 (2002-03-01), None
patent: WO 02/079143 (2002-10-01), None
patent: WO 03/011396 (2003-02-01), None
patent: WO 03/013539 (2003-02-01), None
patent: WO 03/014079 (2003-02-01), None
patent: WO 03/035072 (2003-05-01), None
patent: WO 03/097058 (2003-11-01), None
patent: WO 2004/041259 (2004-05-01), None
patent: WO 2004/045509 (2004-06-01), None
patent: WO 2004/069339 (2004-08-01), None
patent: WO 2005/007166 (2005-01-01), None
patent: WO 2005/102343 (2005-03-01), None
patent: WO 2005/044238 (2005-05-01), None
patent: WO 2005/087207 (2005-09-01), None
patent: WO 2005/102342 (2005-11-01), None
patent: WO 2006/010574 (2006-02-01), None
patent: WO 2006/019715 (2006-02-01), None
patent: WO 2006/096435 (2006-09-01), None
patent: WO 2006/125041 (2006-11-01), None
patent: WO 2007/014929 (2007-02-01), None
patent: WO 2007/048803 (2007-03-01), None
U.S. Appl. No. 11/079,070, Bombarda et al.
U.S. Appl. No. 11/546,303, Bombarda et al.
U.S. Appl. No. 60/658,551, Pyke.
U.S. Appl. No. 60/658,566, Pyke.
U.S. Appl. No. 60/658,611, Pyke.
U.S. Appl. No. 60/734,405, Pyke et al.
Archer, T. “5HT, Pain and Anxiety.” Behavioural Pharmacology of 5-HT (1989), pp. 299-300.
Awouters et al. “Oxatomide, a new orally active drug which inhibits both the release and the effects of allergic mediators.” Chemical Abstracts, vol. 88, No. 15, 88:98788c (Apr. 10, 1978).
Basson et al. “Report of the International Consensus Development Conference on Female Sexual Dysfunction: Definitions and Classifications.” The Journal of Urology, vol. 163 (Mar. 2000), pp. 888-893.
Beers et al., ed. The Merck Manual of Diagnosis and Therapy, 17th ed. (1999), pp. 1595-1598.
Bernstein, J. et al. “Concomitant Polymorphs.” Angewandte Chemise, Int. Ed. (1999), pp. 3441-3461.
Bevan et al. “5-HT and Sexual Behaviour.” Behavioural Pharmacology of 5-HT, pp. 33-34, 87-88 (1989).
Borsini et al. “Behavioral Effects of Flibanserin (BIMT-17),” Pharmacology, Biochemistry and Behavior, vol. 64, issue 1 (Sep. 1999), see abstract.
Borsini et al., Flibanserin, Drugs of the Future, 23(1):9-16 (1998).
Borsini, F. et al. “BIMT-17, a 5HT-2A Receptor Antagonist and 5HT-1A Receptor Full Agonist in Rat Cerebral Cortex,” Naunyn-Schmiedeberg's Archives of Pharm., 352(3):276-82 (1995).
Chalmers et al. “Corticotrophin-releasing Factor Receptors: from Molecular Biology to Drug Design.” TiPS vol. 17 (Apr. 1996), pp. 166-172.
Cloninger, C. R. “A Systematic Method for Clinical Description and Classification of Personality Variants.” Arch. Gen. Psychiatry, vol. 44 (Jun. 1987), pp. 573-588.
Collino, F. et al. Chemical Abstract: Database Accession No. 98:16650-XP 002197885: Mannich bases of benzimidazoles, benzotriazoles and other analogous compounds, with pharmacological activity.
Cools, A. R. “Depression and Psychosis,” Behavioural Pharmacology of 5-HT (1989), pp. 153-155.
Crook, T. & Lakin, M. “Effects of Ondansetron in Age-associated Memory Impairment.” The role of ondansetron, a novel 5-HT3 antagonist, in the treatment of psychiatric disorders, 5th World Congress of Biochemical Psychiatry, pp. 21-23 (1991).
Cyr et al. “Nefazodone: Its Place among Antidepressants.” Annals of Pharmacotherapy 30(9): 1006-12 (1996).
Damour et al. “Preparation and formulation of 1-[(4-phenyl=piperazino)alkyl]benzimidazolin-2-ones and analogs as serotonin S2 antagonists.” Chemical Abstracts, vol. 118, No. 13, 118:124537e (Mar. 29, 1993).
Darlington, C. “Flibanserin.” Current Opinion in CPNS Investigational Drugs, 1(4): 510-13 (1999).
De Angelis. “5-HT2A antagonists in psychiatric disorders.” Current Opinion in Investigational Dru
Bombarda Carlo
Dubini Enrica
Ezhaya Antoine
Schneider, legal representative Margarete
Boehringer Ingelheim Corp
Boehringer Ingelheim Pharma KG
Eyler Yvonne
Nwaonicha Chukwuma O
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