Stable polymeric micelle-type drug composition and method...

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

Reexamination Certificate

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C525S420000, C528S354000, C528S355000, C424S078170, C514S449000, C514S283000, C514S011400, C514S034000, C514S182000, C514S027000, C514S050000

Reexamination Certificate

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10276499

ABSTRACT:
A biocompatible stable composition containing a hydrophobic drug, such as paclitaxel. The composition, which forms a syringeable polymeric micellar solution in aqueous or body fluids, is a freeze-dried product comprising a hydrophobic drug, i.e. paclitaxel, and an amphiphilic block copolymer wherein a hydrophobic group having affinity or attraction with the hydrophobic drug, such as paclitaxel, is incorporated on its end.

REFERENCES:
patent: 5470944 (1995-11-01), Bonsignore
patent: 5683723 (1997-11-01), Spenlehauer et al.
patent: 5702717 (1997-12-01), Cha et al.
patent: 5877205 (1999-03-01), Andersson
patent: 5922754 (1999-07-01), Burchett
patent: 6322805 (2001-11-01), Kim et al.
patent: 6375952 (2002-04-01), Koelle et al.
patent: 0645145 (1997-12-01), None
Kim et al in Polymers for advanced technologies, vol. 10, pp. 647-654 (1999).
Kim et al in Polym. prepa. (Am. Chem. Soc., Div. Polym. Chem) vol. 39 (2), pp. 130-131, 1998.
K. Kataoka, Design of nanoscopic vehicles for drug targeting based on micellization of amphipilic block copolymers, J. Macromol. Sci.-Pure Appl. Chem A31 (1994) 1759-1769.
H. Maeda, The tumor blood vessel as an ideal target for macromolecular anticancer agents, J. Control. Rel. 19(1992) 315-324.
Marie-Christine Jones, Jean-Christophe Leroux, Polymeric micelles—a new generation of colloidal drug carriers, European Journal of Pharmaceuticals and Biopharamceutics 48 (1999) 101-111.
Xichen Zhang, John K. Jackson, Helen M. Burt, Development of amphiphilic diblock copolymers as micellar carriers of taxol, International Journal of Pharmaceutics 132 (1996) 195-206.

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