Stable pharmaceutical compositions containing a fibroblast growt

Details Stable pharmaceutical compositions containing a fibroblast growt Stable pharmaceutical compositions containing a fibroblast growt

1994-10-19

1998-02-03

Walsh, Stephen

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435 691, 435 694, 530350, 530399, A61K 3818, C07K 1450

Patent

active

057144583

ABSTRACT:
A stable lyophilized formulation of a fibroblast growth factor (FGF) comprises the FGF, a pharmaceutically acceptable bulking agent and either

REFERENCES:
patent: 5037644 (1991-08-01), Shaked et al.
patent: 5217954 (1993-06-01), Foster et al.
Budavari et al., eds., The Merck Index, Eleventh Ed., 1989, Merck & Co., Inc., Rahway, NJ, p. 278, No. 1835.
Fox et al., The Journal of Biol. Chem., vol. 263, pp. 18452-18458, 1988.
R.R. Lobb, "Clinical Applications of Heparin-Binding Growth Factors, "European Journal of Clinical Investigations, vol. 18 (1988), pp. 321-336.
D. Gospedarowicz et al, "Heparin Protects Basic and Acidic FGF From Inactivation, "Journal of Cellular Physiology, vol. 128 (1986), pp. 475-484.
Abraham et al., 1986, Embo J. 5, 2523.

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