Stable perfluorocarbon and oil emulsions

Details Stable perfluorocarbon and oil emulsions Stable perfluorocarbon and oil emulsions

1990-11-09

1996-07-16

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Halogenated hydrocarbon doai

A61K 3103

Patent

active

055367534

ABSTRACT:
Perfluoroindane is used as a gas transport agent in animals without causing gas or vapor pulmonary embolism. Emulsions containing perfluoroindane as the oxygen carrying component are made and infused into an animal and the perfluoroindane escapes at a very rapid rate from the animal body. The perfluoroindane-containing liquids or emulsions are considered valuable for angioplasty and as a blood substitute.

REFERENCES:
patent: 3911138 (1975-10-01), Clark, Jr.
patent: 4105798 (1978-08-01), Moore et al.
patent: 4289499 (1981-09-01), Clark et al.
patent: 4395393 (1983-07-01), Schmolka
patent: 4439424 (1984-03-01), Ecanow et al.
patent: 4443480 (1984-04-01), Clark, Jr.
patent: 4461717 (1984-07-01), Moore
"The Synthesis and Biological Screening of New and Improved Fluorocarbon Compounds for Use as Artificial Blood Substitutes", Final Report prepared under Contract # 14B6-2927 for the period Jun. 30, 1976-Dec. 31, 1978 by Robert E. Moore, as Prepared for the National Institutes of Health.
Yamanouchi, Kouichi et al, Chem. Pharm. Bull., 33(3) 1221-1231 (1985) "Quantitative Structure in Vivo Half-life Relationships of Perfluoro-chemicals for use as Oxygen Transporters".

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