Stable parenteral solution of 2-phenyl-1.2-benzisoselenazol-3(2H

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3141

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052887340

ABSTRACT:
The present invention is related to new parenteral preparations of 2-phenyl-1.2-benzisoselenazol-3(2H)-one (Ebselen) comprising additionally one or several phospholipids and, possibly, one or several auxiliary agents. The invention is further related to a process for producing such solutions and their use in the preparation of drug preparations ob Ebselen.

REFERENCES:
patent: 4352799 (1982-10-01), Renson et al.
patent: 4711961 (1987-12-01), Welter
patent: 4784994 (1988-11-01), Romer et al.
patent: 47788156 (1988-10-01), Cash
Handbook of Pharmaceutical Excipients, p 165, A.P.A. Wash. D.C. 1986.
Bulletin de la Soc. Chim. de France, 1976 (7/8), S. 1124-1126.

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