Stable oral compositions comprising casein phosphopeptide...

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

Reexamination Certificate

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Reexamination Certificate

active

06863882

ABSTRACT:
The present invention relates to oral care compositions, especially toothpastes, comprising: a safe and effective amount of phosphopeptide-amorphous calcium phosphate complex (“PP-ACP”); a safe and effective amount of a fluoride ion source; a pharmaceutically-acceptable topical, oral carrier, and a safe and effective amount of a calcium chelator, wherein the composition has improved fluoride stability. This invention further relates to a method of maintaining the fluoride levels in an oral care composition comprising a safe and effective amount of PP-ACP, a safe and effective amount of a fluoride ion source, and a pharmaceutically-acceptable topical, oral carrier, by adding, to the composition, a safe and effective amount of a calcium chelator.

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