Stable oral CI-981 formulation and process of preparing same

Details Stable oral CI-981 formulation and process of preparing same Stable oral CI-981 formulation and process of preparing same

1994-05-20

1997-11-11

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424465, 424683, 424692, 424693, 424715, 424489, 514824, A61K 916, A61K 920, A61K 948, A61K 4702

Patent

active

056861044

ABSTRACT:
An oral pharmaceutical composition is provided for treating hypercholestereolemia or hyperlipidemia containing an advantageous formulation for stabilizing the HMG-CoA coenzyme A inhibitor, CI-981 Hemi-Calcium, of formula (IA) ##STR1## with effective amounts of calcium carbonate. A method for preparing a CI-981 stabilizing composition is described.

REFERENCES:
patent: 4681893 (1987-07-01), Roth
patent: 5030447 (1991-07-01), Mills et al.

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