Stable non-aqueous single phase viscous vehicles and...

Details Stable non-aqueous single phase viscous vehicles and... Stable non-aqueous single phase viscous vehicles and...

2007-08-21

2007-08-21

Hartley, Michael G. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S449000, C424S423000, C514S937000

Reexamination Certificate

active

09497422

ABSTRACT:
This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7reciprocal second.

REFERENCES:
patent: 2110208 (1938-03-01), Eggert
patent: 3632768 (1972-01-01), Bergy et al.
patent: 4078060 (1978-03-01), Benson et al.
patent: 4376118 (1983-03-01), Daher et al.
patent: 4734284 (1988-03-01), Takashi et al.
patent: 4927687 (1990-05-01), Nuwayser
patent: 4952402 (1990-08-01), Sparks et al.
patent: 5034229 (1991-07-01), Magruder et al.
patent: 5057318 (1991-10-01), Magruder et al.
patent: 5071642 (1991-12-01), Hein-Uwe et al.
patent: 5110596 (1992-05-01), Magruder et al.
patent: 5284655 (1994-02-01), Bogdansky et al.
patent: 5290271 (1994-03-01), Jernberg
patent: 5371089 (1994-12-01), Rattan
patent: 5374620 (1994-12-01), Clark et al.
patent: 5385738 (1995-01-01), Yoshiya et al.
patent: 5540912 (1996-07-01), Roorda et al.
patent: 5668170 (1997-09-01), Gyory
patent: 5747058 (1998-05-01), Tipton et al.
patent: 5756450 (1998-05-01), Lorenz et al.
patent: 5782396 (1998-07-01), Mastri et al.
patent: 5814323 (1998-09-01), Lyle
patent: 5843891 (1998-12-01), Sherman
patent: 5882676 (1999-03-01), Lee et al.
patent: 5906830 (1999-05-01), Farinas et al.
patent: 5928666 (1999-07-01), Farinas et al.
patent: 5972373 (1999-10-01), Yajima et al.
patent: 6331311 (2001-12-01), Brodbeck et al.
patent: 0 265 848 (1991-09-01), None
patent: 1049104 (1966-11-01), None
patent: WO96 39142 (1996-12-01), None
patent: WO 97/28181 (1997-08-01), None
patent: 98/16250 (1998-04-01), None
patent: WO 98/27960 (1998-07-01), None
patent: WO98 27962 (1998-07-01), None
patent: WO98 27963 (1998-07-01), None
Bell et al, “Impact of Moisture on Thermally Induced . . . ,” Drug Deliv. Res. & Dev., John Wiley & Sons, Inc. (U.S.A.), p. S4-S26, 1995.
Chang et al, “Biodegradeable Polyester Implants . . . , ” Pharm. Tech., p. 80-84, 1996.
Desai et al., “Protein Structure in the Lyophilized . . .” J. Amer. Chem. Soc.,p. 9420-9422, 1994.
Hageman, Michael J., “The Role of Moisture in Protein Stability, ” Drug Dev. & Ind. Pharm., vol. 14 (No. 14), p. 2047-2070, 1988.
Knepp et al, “Stability of Nonaqueous Suspension . . . ,” Pharm. Res., vol. 15 (No. 7), p.1090-1095, 1998.
Knepp et al, “,” J. Pharm. Sci. Tech., p. 163-171. vol. 50, No. 3, 1996.
Manning et al, “Stahility of Protein . . . ,” Pharm. Res., vol. 6 (No. 11), p. 903-918, 1989.
Wang et al, “Parenteral Formulations . . . ,” J. Parenteral Sci. Tech., p. S4-S26, 1988.
Yu et al, “Preparation, Characterization, and . . . ,” J. Pharm. Sci., vol. 85 (No. 4), p. 396-401, 1996.
Zhang et al, “A New Strategy . . . ,” Pharm Res., vol. 12 (No. 10), p. 1447-1452,1995.
Ansel et al., “Seventh Ed., Pharmaceutical Dosage Forms and Drug Delivery Systems,” Lippincott Williams & Wilkins (date unknown) pp. 88-90.
Cas RN 56-81-5, Nov. 16, 1984.
Int J Radiat Biol 1995 Jan; 67(1):57-64.
J Toxicol Sci 1993 Aug: 18 Supp 3:1-9.
“Modified-Release Dosage Forms and Drug Delivery Systems,” (date unknown), pp. 229,236,242 & 243.
Transplantation 1989 Oct; 48(4);554-8

Affiliated with

Also associated with

Rating

Stable non-aqueous single phase viscous vehicles and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stable non-aqueous single phase viscous vehicles and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stable non-aqueous single phase viscous vehicles and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3831107