Stable non-aqueous single phase viscous vehicles and...

Details Stable non-aqueous single phase viscous vehicles and... Stable non-aqueous single phase viscous vehicles and...

2011-04-05

2011-04-05

Fubara, Blessing M (Department: 1613)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C514S772000, C514S772300, C514S784000, C514S785000

Reexamination Certificate

active

07919109

ABSTRACT:
This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7reciprocal second.

REFERENCES:
patent: 2110208 (1938-03-01), Eggert
patent: 3632768 (1972-01-01), Bergy et al.
patent: 3869549 (1975-03-01), Geller
patent: 4078060 (1978-03-01), Benson et al.
patent: 4310516 (1982-01-01), Chang et al.
patent: 4376118 (1983-03-01), Daher et al.
patent: 4588614 (1986-05-01), Lauchenauer
patent: 4594108 (1986-06-01), Greminger, Jr. et al.
patent: 4734284 (1988-03-01), Terada et al.
patent: 4927687 (1990-05-01), Nuwayser
patent: 4952402 (1990-08-01), Sparks et al.
patent: 5034229 (1991-07-01), Magruder et al.
patent: 5057318 (1991-10-01), Magruder et al.
patent: 5071642 (1991-12-01), Lahr et al.
patent: 5110596 (1992-05-01), Magruder et al.
patent: 5120712 (1992-06-01), Habener
patent: 5284655 (1994-02-01), Bogdansky et al.
patent: 5290271 (1994-03-01), Jernberg
patent: 5300302 (1994-04-01), Tachon et al.
patent: 5352662 (1994-10-01), Brooks et al.
patent: 5371089 (1994-12-01), Rattan
patent: 5374620 (1994-12-01), Clark et al.
patent: 5385738 (1995-01-01), Yamahira et al.
patent: 5411951 (1995-05-01), Mitchell
patent: 5424286 (1995-06-01), Eng
patent: 5512293 (1996-04-01), Landrau et al.
patent: 5540912 (1996-07-01), Roorda et al.
patent: 5545618 (1996-08-01), Buckley et al.
patent: 5571525 (1996-11-01), Roorda et al.
patent: 5574008 (1996-11-01), Johnson et al.
patent: 5614221 (1997-03-01), Fjellstrom
patent: 5635213 (1997-06-01), Nystrom et al.
patent: 5668170 (1997-09-01), Gyory
patent: 5728396 (1998-03-01), Peery, Jr. et al.
patent: 5747058 (1998-05-01), Tipton et al.
patent: 5756450 (1998-05-01), Hahn et al.
patent: 5782396 (1998-07-01), Mastri et al.
patent: 5814323 (1998-09-01), Lyle
patent: 5843891 (1998-12-01), Sherman
patent: 5882676 (1999-03-01), Lee et al.
patent: 5904935 (1999-05-01), Eckenhoff et al.
patent: 5906830 (1999-05-01), Farinas et al.
patent: 5928666 (1999-07-01), Farinas et al.
patent: 5932547 (1999-08-01), Stevenson et al.
patent: 5958909 (1999-09-01), Habener
patent: 5972370 (1999-10-01), Eckenhoff et al.
patent: 5972373 (1999-10-01), Yajima et al.
patent: 5985305 (1999-11-01), Peery, Jr. et al.
patent: 5997527 (1999-12-01), Gumucio et al.
patent: 6017545 (2000-01-01), Modi
patent: 6113938 (2000-09-01), Chen et al.
patent: 6124261 (2000-09-01), Stevenson et al.
patent: 6127520 (2000-10-01), Ueda et al.
patent: 6130200 (2000-10-01), Brodbeck et al.
patent: 6132420 (2000-10-01), Dionne et al.
patent: 6156331 (2000-12-01), Peery, Jr. et al.
patent: 6218431 (2001-04-01), Schoen et al.
patent: 6235712 (2001-05-01), Stevenson et al.
patent: 6261584 (2001-07-01), Peery, Jr. et al.
patent: 6270787 (2001-08-01), Ayer
patent: 6287295 (2001-09-01), Chen et al.
patent: 6331311 (2001-12-01), Brodbeck et al.
patent: 6375978 (2002-04-01), Kleiner et al.
patent: 6395292 (2002-05-01), Peery, Jr. et al.
patent: 6468961 (2002-10-01), Brodbeck et al.
patent: 6508808 (2003-01-01), Carr et al.
patent: 6524305 (2003-02-01), Peterson et al.
patent: 6544252 (2003-04-01), Theeuwes et al.
patent: 6635268 (2003-10-01), Peery, Jr. et al.
patent: 6673767 (2004-01-01), Brodbeck et al.
patent: 6939556 (2005-09-01), Lautenbach
patent: 7014636 (2006-03-01), Gilbert
patent: 7074423 (2006-07-01), Fereira et al.
patent: 7163688 (2007-01-01), Peery et al.
patent: 7207982 (2007-04-01), Dionne et al.
patent: 7258869 (2007-08-01), Berry et al.
patent: 7655257 (2010-02-01), Peery, Jr. et al.
patent: 2002/0034532 (2002-03-01), Brodbeck et al.
patent: 2003/0044467 (2003-03-01), Brodbeck et al.
patent: 2003/0211974 (2003-11-01), Brodbeck et al.
patent: 2004/0224903 (2004-11-01), Berry et al.
patent: 2005/0008661 (2005-01-01), Fereira et al.
patent: 2005/0112188 (2005-05-01), Eliaz et al.
patent: 2005/0175701 (2005-08-01), Pan et al.
patent: 2005/0266087 (2005-12-01), Junnarkar et al.
patent: 2005/0276856 (2005-12-01), Fereira et al.
patent: 2006/0013879 (2006-01-01), Brodbeck et al.
patent: 2006/0141040 (2006-06-01), Chen et al.
patent: 2006/0142234 (2006-06-01), Chen et al.
patent: 2006/0193918 (2006-08-01), Rohloff et al.
patent: 2006/0216242 (2006-09-01), Rohloff et al.
patent: 2006/0246138 (2006-11-01), Rohloff et al.
patent: 2007/0027105 (2007-02-01), Junnarkar et al.
patent: 2007/0281024 (2007-12-01), Lautenbach et al.
patent: 0265848 (1991-09-01), None
patent: 0379147 (1994-09-01), None
patent: 1049104 (1966-11-01), None
patent: 95/34285 (1995-12-01), None
patent: 96/39142 (1996-12-01), None
patent: 96/40049 (1996-12-01), None
patent: 97/28181 (1997-08-01), None
patent: 98/00152 (1998-01-01), None
patent: 98/00157 (1998-01-01), None
patent: 98/00158 (1998-01-01), None
patent: 98/16250 (1998-04-01), None
patent: 98/27960 (1998-07-01), None
patent: 98/27962 (1998-07-01), None
patent: 98/27963 (1998-07-01), None
Perry, J.R., et al., U.S. Appl. No. 60/122,056, which was originally filed as U.S. Appl. No. 08/595,761 on Feb. 2, 1996, including the Filing Receipt, and the “Notice of Reassign Application Number.”
Bell et al, “Impact of Moisture on Thermally Induced . . . ,” Drug Deliv. Res. & Dev., John Wiley & Sons, Inc. (U.S.A.), p. S4-S26, 1995.
Bertoncello et al., “Haematopoietic radioprotection by Cremophor EL: a polyethoxylated castor oil,” Int J Radiat Biol, vol. 67 (No. 1), p. 57-64, 1995.
Cas RN 56-81-5, Nov. 16, 1984.
Chang et al, “Biodegradeable Polyester Implants . . . , ” Pharm. Tech., p. 80-84, 1996.
Desai et al., “Protein Structure in the Lyophilized . . . ” J. Amer. Chem. Soc., p. 9420-9422, 1994.
Hageman, Michael J., “The Role of Moisture in Protein Stability,” Drug Dev. & Ind. Pharm., vol. 14 (No. 14), p. 2047-2070, 1988.
Hisatomi et al., “Toxicity of polyoxyethylene hydrogenated castor oil 60 (HCO-60) in experimental animals,”J Toxicol Sci, Aug. 1993: 18 Supp 3:1-9.
Introduction to Antibodies downloaded from the world wide web on May 2, 2007; http://www.chemicon.com/resource/ANT101/a1.asp.
Knepp et al, “Identification of antioxidants for prevention of peroxide-mediated oxidation of recombinant human ciliary neurotrophic factor and recombinant human nerve growth factor,” J. Pharm. Sci. Tech., p. 163-171. vol. 50, No. 3, 1996.
Knepp et al, “Stability of Nonaqueous Suspension . . . ,” Pharm. Res., vol. 15 (No. 7), p. 1090-1095, 1998.
Manning et al, “Stability of Protein . . . ,” Pharm. Res., vol. 6 (No. 11), p. 903-918, 1989.
Roman et al., “Cholestasis in the rat by means of intravenous administration of cyclosporine vehicle, Cremophor EL,” Transplantation, Oct. 1989, 48(4), p. 554-8.
Wang et al, “Parenteral Formulations . . . ,” J. Parenteral Sci. Tech., p. S4-S26, 1988.
Yu et al, “Preparation, Characterization, and . . . ,” J. Pharm. Sci., vol. 85 (No. 4), p. 396-401, 1996.
Zhang et al, “A New Strategy . . . ,” Pharm Res., vol. 12 (No. 10), p. 1447-1452,1995.

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