Stable microbubbles suspensions injectable into living organisms

Details Stable microbubbles suspensions injectable into living organisms Stable microbubbles suspensions injectable into living organisms

1995-06-01

1996-10-22

Dees, Jose G.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Ultrasound contrast agent

A61K 4900

Patent

active

055674143

ABSTRACT:
Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophillc stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.

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Chemical Abstracts, vol. 102, No. 3, 21 Jan. 1985. Maynard et al "Ultrasonic absorption by liposomes", see p. 291, #20001d.

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