Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent
Patent
1994-09-30
1996-07-02
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Ultrasound contrast agent
424 951, A61K 4900
Patent
active
055319807
ABSTRACT:
Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.
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Chemical Abstracts, vol. 102, No. 3, 21 Jan. 1985. Maynard et al "Ultrasonic absorption by liposomes", see page 291, #20001d.
Bichon Daniel
Bussat Philippe
Hybl-Sutherland Eva
Puginier Jerome
Schneider Michel
Bracco International BV
Cebulak Mary C.
Robinson Allen J.
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