Stable microbubbles suspensions injectable into living organisms

Details Stable microbubbles suspensions injectable into living organisms Stable microbubbles suspensions injectable into living organisms

1993-09-29

1995-01-10

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

424450, 514975, 12866202, A61B 808, A61B 814, A61K 3722

Patent

active

053805194

ABSTRACT:
Gas or air filled microbubble suspensions in aqueous phase usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.

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Chemical Abstracts, vol. 102, No. 3, 21 Jan. 1985. Maynard et al.: "Ultrasonic absorption by liposomes", see p. 291, #20001d.

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