Stable microbubbles suspensions injectable into living organisms

Details Stable microbubbles suspensions injectable into living organisms Stable microbubbles suspensions injectable into living organisms

1998-02-11

1999-06-15

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Ultrasound contrast agent

424 952, A61B 813

Patent

active

059119721

ABSTRACT:
Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.

REFERENCES:
patent: 4256251 (1981-03-01), Moshofsky
patent: 4276885 (1981-07-01), Tickner et al.
patent: 4316391 (1982-02-01), Tickner
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4572203 (1986-02-01), Feinstein
patent: 4657756 (1987-04-01), Rasor et al.
patent: 4681119 (1987-07-01), Rasor et al.
patent: 4684479 (1987-08-01), D'Arrigo
patent: 4718433 (1988-01-01), Feinstein
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4844882 (1989-07-01), Widder et al.
patent: 4900540 (1990-02-01), Ryan et al.
patent: 4957656 (1990-09-01), Cerny et al.
patent: 5088499 (1992-02-01), Unger
patent: 5137928 (1992-08-01), Erbel et al.
patent: 5141738 (1992-08-01), Rasor et al.
patent: 5147631 (1992-09-01), Glajch et al.
patent: 5271928 (1993-12-01), Schneider et al.
patent: 5352436 (1994-10-01), Wheatley et al.
patent: 5380519 (1995-01-01), Schneider et al.
patent: 5409688 (1995-04-01), Quay
patent: 5425366 (1995-06-01), Reinhardt et al.
patent: 5501863 (1996-03-01), Rossling et al.
patent: 5531980 (1996-07-01), Schneider et al.
patent: 5536489 (1996-07-01), Lohrmann et al.
patent: 5536490 (1996-07-01), Klaveness et al.
patent: 5567414 (1996-10-01), Schneider et al.
patent: 5599523 (1997-02-01), Beller et al.
patent: 5643553 (1997-07-01), Schneider et al.
patent: 5658551 (1997-08-01), Schneider et al.
Swanson, pp. 682-687 "Chapter 22: Enhancement Agents for Ultrasound: Fundamentals" in Pharmaceuticals In Medical Imaging, (EDS. Swanson et al., MacMillan Publishing Company, New York, 1990).
Lincoff et al Intravitreal Longevity of Three Perfluorocarbon Gases, Arch. Ophthalmology, 98: 1610-1661(1980).
Lincoff et al Intravitreal Expansion of Pefluorocarbon Bubbles, Arch. Ophthalmology, 98:1646 (1980).
Lincoff et al The Perfluorocarbon Gases in the Treatment of Retinal Detachment, Ophthalmology, 90(5):546-551(1983).
Lincoff et al Perfluoro-n-butane: A Gas for Maximum Duration Retinal Tamponade, Arch Ophthalmology, 101:460-463(1983).
Gardner et al (1988) "A Survey of Intraocular Gas Use in North America," Arch Ophthalmol. 106:1188-1189.

Affiliated with

Also associated with

Rating

Stable microbubbles suspensions injectable into living organisms does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stable microbubbles suspensions injectable into living organisms, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stable microbubbles suspensions injectable into living organisms will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-400846