Stable microbubbles suspensions injectable into living...

Details Stable microbubbles suspensions injectable into living... Stable microbubbles suspensions injectable into living...

2006-04-25

2006-04-25

Hartley, Michael (Department: 1618)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Ultrasound contrast agent

C424S009510

Reexamination Certificate

active

07033574

ABSTRACT:
Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.

REFERENCES:
patent: 4256251 (1981-03-01), Moshofsky
patent: 4276885 (1981-07-01), Tickner et al.
patent: 4316391 (1982-02-01), Tickner
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4572203 (1986-02-01), Feinstein
patent: 4657756 (1987-04-01), Rasor et al.
patent: 4681119 (1987-07-01), Rasor et al.
patent: 4684479 (1987-08-01), D'Arrigo
patent: 4718433 (1988-01-01), Feinstein
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4844882 (1989-07-01), Widder et al.
patent: 4900540 (1990-02-01), Ryan et al.
patent: 4957656 (1990-09-01), Cerny et al.
patent: 5088499 (1992-02-01), Unger
patent: 5137928 (1992-08-01), Erbel et al.
patent: 5141738 (1992-08-01), Rasor et al.
patent: 5147631 (1992-09-01), Glajch et al.
patent: 5425366 (1995-06-01), Reinhardt et al.
patent: 5501863 (1996-03-01), Rossling et al.
patent: 5599523 (1997-02-01), Beller et al.
patent: 40651/89 (1990-03-01), None
patent: 70982/91 (1991-10-01), None
patent: 1232837 (1988-02-01), None
patent: 1239092 (1988-07-01), None
patent: 0122624 (1984-10-01), None
patent: 0131540 (1985-10-01), None
patent: 0327490 (1989-08-01), None
patent: 0441468 (1990-02-01), None
patent: 0357163 (1990-03-01), None
patent: 0494615 (1992-07-01), None
patent: 0123235 (1994-10-01), None
patent: WO 90/01952 (1990-03-01), None
patent: WO91/12823 (1991-09-01), None
patent: WO92/18164 (1992-10-01), None
patent: WO93/05819 (1993-04-01), None
patent: 84/2800 (1984-04-01), None
Swanson, pp. 682-687 “Chapter 22: Enhancement Agents for Ultrasound: Fundamentals” in Pharmaceuticals in Medical Imaging, (EDS. Swanson et al., MacMillan Publishing Company, New York, 1990).
Lincoff et alIntravitreal Longevity of Three Perfluorocarbon Gases, Arch. Ophthalmology, 98: 1610-1611 (1980).
Lincoff et alIntravitreal Expansion of Pefluorocarbon Bubbles, Arch. Ophthalmology, 98: 1646 (1980).
Lincoff et alThe Perfluorocarbon Gases in the Treatment of Retinal Detachment, Ophthalmology, 90(5):546-551 (1983).
Lincoff et alPerfluoro-n-butane: A Gas for Maximum Duration Retinal Tamponade, Arch. Ophthalmology, 101:460-463 (1983).
Gardner et al. (1988) “A Survey of Intraocular Gas Use in North America,”Arch Ophthalmol.106:1188-1189.

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