Stable liquid composition containing urate oxidase and lyophiliz

Details Stable liquid composition containing urate oxidase and lyophiliz Stable liquid composition containing urate oxidase and lyophiliz

1996-05-10

1998-09-22

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Oxidoreductases

424 943, A61K 3844

Patent

active

058110968

ABSTRACT:
The invention relates to a physically stable, pharmaceutically acceptable liquid composition containing urate oxidase, and from 0.1 mg/ml to 10 mg/ml of Poloxamer 188, in buffered aqueous medium. This composition can be obtained by dissolving a lyophilibate in an aqueous solvent.

REFERENCES:
patent: 3928137 (1975-12-01), Monte et al.
patent: 3997470 (1976-12-01), Monte et al.

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