Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-09-29
1999-12-28
Campell, Bruce R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 1, 424450, A61K 9127, A61K 3100, A61K 4800
Patent
active
06008202&
ABSTRACT:
Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the prior art admixture method and upon purification, the complexes produced by the method of this invention are 50 to 500 fold more concentrated than the complexes formed by admixture. The method described herein provides for the large scale production of lipid-comprising drug delivery systems useful for gene therapy and other applications.
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Gao Xiang
Huang Leaf
Loomis Aaron Garth
Paul Ralph Wilfred
Sloane David L.
Campell Bruce R.
Targeted Genetics Corporation
University of Pittsburgh
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