Stable lipid-comprising drug delivery complexes and methods for

Details Stable lipid-comprising drug delivery complexes and methods for Stable lipid-comprising drug delivery complexes and methods for

1995-01-23

1998-08-18

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

935 54, A61K 9127

Patent

active

057955875

ABSTRACT:
Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the prior art admixture method and upon purification, the complexes produced by the method of this invention are 50 to 500 fold more concentrated than the components of the complexes formed by admixture. The method described herein provides for the large scale production of lipid-comprising drug delivery systems useful for gene therapy and other applications.

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