Stable immunogen composition for oral administration

Drug – bio-affecting and body treating compositions – Lymphokine

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424 89, 424 92, 424492, 530350, 530395, 530413, 530416, 530427, 530806, A61K 3900, A61K 916

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active

051769093

ABSTRACT:
A stable immunogen composition for oral administration which includes a dried spherical form comprised of an immunogen capable of immunizing human or animals and a gelatin having an average molecular weight of 80,000-120,000 and jelly strength of more than 150 (Bloom, g, 6.2/3%), and is enteric.

REFERENCES:
patent: 4376113 (1983-03-01), Suglia et al.
patent: 4987031 (1991-01-01), Tatematsu et al.
M. Kurokawa, S. Ishida, R. Murata, A. Oya, T. Sawada, S. Kameyama, and S. Ohtani "Accelerated degradation tests on some immunological products", 1979, pp. 31-41.
Ker-Sang Chen and Gerald V. Quinnan, Jr., "Secretory Immunoglobulin A Antibody Response Is Conserved in Aged Mice following Oral Immunization with Influenza Virus Vaccine", 1989, pp. 3291-3296.
Robert H. Waldman, Karl-Christian Bergmann, Judy Stone, Stephen Howard, Vince Chiodo, Arthur Jacknowitz, Elizabeth R. Waldman, and Rashida Khakoo, "Age-Dependent Antibody Response in Mice and Humans Following Oral Influenza Immunization", 1987, pp. 327-332.

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