Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1995-06-07
1998-05-12
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
424 141, 530300, 530317, 530323, 530332, 544238, 546281, A61K 5108, A61K 3800, C07D40100
Patent
active
057500886
ABSTRACT:
This invention provides novel reagents for the preparation of radiopharmaceuticals useful as imaging agents for the diagnosis of cardiovascular disorders, infection, inflammation and cancer, diagnostic kits comprising said reagents and intermediate compounds useful for the preparation of said reagents. The reagents are comprised of stable hydrazone modified biologically active molecules that react with gamma emitting radioisotopes to form radiopharmaceuticals that selectively localize at sites of disease and thus allow an image to be obtained of the loci using gamma scintigraphy.
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Cheesman Edward Hollister
Edwards David Scott
Harris Thomas David
Liu Shuang
Rajopadhye Milind
Boudreaux Gerald J.
Hartley Michael G.
Hollinden Gary E.
The DuPont Merck Pharmaceutical Company
Vance David H.
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