Stable high-concentration injection containing pyrazolone...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

10477275

ABSTRACT:
An injection which contains as the active ingredient a pyrazolone derivative which typically is Edaravone, a physiologically acceptable salt thereof, or a hydrate or solvate of either in an amount of 3 to 60 mg/mL. It is excellent in long-term stability, product storage, and suitability for use.

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Singhai et al., “Cosolvent solubilization and formulation of an aqueous injection of ketoprofen,”Pharmazie, 51 (10), 737-740 (1996).

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