Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Elemental iodine or iodine compound
Patent
1998-09-30
2000-11-28
Cook, Rebecca
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Elemental iodine or iodine compound
424667, 424670, 424671, 514738, A01N 5922
Patent
active
061532290
ABSTRACT:
Stable aqueous glycerin iodine concentrates are provided which are adapted for dilution in water to yield germicidal iodine use solutions. The concentrates include from about glycerin, iodine, and iodide ion. Preferably, the concentrates further include one or more additives such as compatible wetting agents, hydrotropes, thickening agents, additional emollients and buffering systems. The quantities of iodide ion and iodine are such that the ratio of iodide ion to iodine is from about 0.5:1 to about 6:1. The concentrates are stable for a period of at least about 3 months at room temperature and are dilutable at a ratio of 1 part concentrate with from about 2-80 parts water. The concentrates can be formulated to give very low free iodine values as concentrates which dramatically increase in diluted use solutions to values which are from about 2 to about 300 times greater than the free iodine in the concentrates.
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Godinho et al.; The Interaction of Glycerol and an Iodophor Teat Dip; J. Appl. Bacteriol., 48:449-455 (1980).
Osol et al,; Solubility of Iodine in Glycol-Water solutions; J. Amer.Pharm.Assn.; 41:634 (1952).
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Cook Rebecca
West Agro Inc.
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