Stable drug form for oral administration with benzimidazole...

Details Stable drug form for oral administration with benzimidazole... Stable drug form for oral administration with benzimidazole...

2007-10-02

2007-10-02

Tran, S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S464000, C424S471000, C424S474000, C424S480000, C424S489000, C424S490000, C424S494000, C424S472000

Reexamination Certificate

active

11502830

ABSTRACT:
The invention relates to a stable medicament for oral administration which comprises(a) a core which contains an active ingredient selected from Omeprazole, Lansoprazole and Pantoprazole, together with customary pharmaceutical adjuvants,(b) an intermediate layer applied onto the core, and(c) a gastric juice-resistant outer layer. The intermediate layer in (b) is formed as a reactive layer in which a gastric juice-resistant polymer layer material partially neutralized with alkali with cation exchange capacity is present.Further, a method for the production of the stable medicament is disclosed.

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Übcrzogene Arzneiformen, by Bauer et al.; Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, 1998, pp. 88-89.

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