Stable digestive enzyme compositions

Details Stable digestive enzyme compositions Stable digestive enzyme compositions

2009-10-09

2010-02-09

Hobbs, Lisa J (Department: 1657)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C424S479000, C424S094210

Reexamination Certificate

active

07658918

ABSTRACT:
Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing.

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