Stable D-dimer liquid preparation

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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Details

C436S015000

Reexamination Certificate

active

08071723

ABSTRACT:
The invention is in the field of coagulation diagnosis and relates to a liquid, buffer-based D-dimer composition, which additionally contains fibrinogen and which is suitable as a standard material for control or calibration purposes for D-dimer test procedures.

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Whitaker, A.N. et al., “Measurement of cross linked fibrin derivatives in plasma: an immunoassay using monoclonal antibodies,” J. Clin. Pathol. 37: 882-7 (1984).
Dempfle, “D-dimer testing and venous thromboembolism: four view points,”J. of Thrombosis and Haemostasis, 3: 377-379 (2005).
Edlund, “A proposed stoichiometrical calibration procedure to achieve transferability of D-dimer measurements and to characterize the performance of different methods,”Clinical Biochemistry, 39: 137-142 (2006).

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