Stable, cosmetically acceptable topical gel formulation and meth

Details Stable, cosmetically acceptable topical gel formulation and meth Stable, cosmetically acceptable topical gel formulation and meth

1989-06-27

1992-06-16

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

3,10-dihydroxy-2-naphthacene carboxamide or derivative doai

514944, A61K 3165

Patent

active

051225190

ABSTRACT:
Stable, cosmetically acceptable gel formulations of the tetracycline antibiotics for the topical treatment of acne in humans. Minocycline hydrochloride is the preferred antibiotic and the pharmaceutical vehicle is a volatile silicone solvent in combination with an emollient ester cosolvent and a polyethylene gelling agent.

REFERENCES:
patent: 4058491 (1977-11-01), Steckler
patent: 4140656 (1979-02-01), Mast
patent: 4411893 (1983-10-01), Johnson et al.
Chemical Abstracts, 97:3459v (1982).

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