Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Patent
1997-10-17
1999-08-10
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
252309, 252312, 424 59, 424 60, 424400, 514938, 514944, A61K 700, A61K 744, B01J 1300
Patent
active
059355891
ABSTRACT:
The inventive compositions contain an oil-in-water and a water-in-oil emulsion, each buffered to a specific pH, so that the difference in pH values of the two emulsions is at least two units. The molecular mixing is minimized by selecting suitable oil and oil phase in a water-in-oil emulsion. The change in pH is further minimized by buffering each emulsion. The particular advantage of the inventive compositions is the ability to separate within a single composition, with minimal intermixing, active compounds which require different pH environments for stability and/or optimum efficacy.
REFERENCES:
patent: 5332595 (1994-07-01), Gaonkar
Fox, "An Introduction to Multiple Emulsions" Cosmetics and Toiletry, vol. 101, Nov., 1986, pp. 101-112.
Habif Stephan
Mukherjee Surajit
Rick Donald
Chesebrough-Pond's USA Co.
Dodson Shelley A.
Mitelman Rimma
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