Stable congener of 2',3'-dideoxyadenosine

Details Stable congener of 2',3'-dideoxyadenosine Stable congener of 2',3'-dideoxyadenosine

1989-04-26

1991-05-07

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, C07H 19173

Patent

active

050138294

ABSTRACT:
The preseent invention is concerned with congeners of 2',3'-dideoxyadenosine (ddA) with modifications at the 2- and 8- positions to increase stability of the compounds from the standpoint of resistance to deamination and hydrolytic cleavage of the glycosidic bond.

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