Stable clumping factor for the identification of fibrinogen and

Details Stable clumping factor for the identification of fibrinogen and Stable clumping factor for the identification of fibrinogen and

1976-06-08

1981-01-13

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

435253, 435260, 435883, C12Q 156, C12N 120, C12R 1445

Patent

active

042450390

ABSTRACT:
A homogeneous suspension, in a buffered aqueous solution having a pH of 7.0 to 7.7, of a destroyed microorganism which is positive to the clumping factor, said suspension containing from 3 to 50 percent by weight of at least one polyhydric alcohol soluble therein, is disclosed, as are its manufacture and its use as a reagent for the determination of fibrinogen and for fibrin cleavage products.

REFERENCES:
patent: 3843453 (1974-10-01), Freake
patent: 3853710 (1974-12-01), Innerfield
patent: 3983004 (1976-09-01), Trobish et al.
patent: 3990947 (1976-11-01), Butler et al.
Hawiger et al., "Measurement of Fibrinogen and Fibrin Degradation Products in Serum by Staphylococcal Clumping Test", J. Lab. Clin. Med., vol. 75, No. 1, pp. 93-108, (1970).
Duthie, "The Action of Fibrinogen on Certain Pathogenic Cocci", J. Gen. Microbiol., vol. 13, pp. 383-393, (1955).
Thomas et al., "A Comparative Study of Four Methods for Detecting Fibrinogen Degradation Products in Patients with Various Diseases", The New England Journal of Medicine, vol. 283, No. 13, pp. 663-668, (1970).
Microbiology Abstracts, 3A (1967.12) 3, p. 124.

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