Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2008-07-29
2008-07-29
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S006120, C435S320100, C435S069100, C435S325000, C435S348000, C435S455000, C435S456000
Reexamination Certificate
active
07405038
ABSTRACT:
Cell lines that are commonly used for protein expression are engineered to include genes that encode suppressors of apoptosis (SA). Insect cell lines expressing these SA genes are resistant to apoptosis or programmed cell death, and express certain recombinant proteins at increased levels. These cell lines also have increased resistance to many types of stress. Because some of the SA proteins inhibit apoptosis in a wide spectrum of organisms, these genes may be inserted into other plant or animal cell lines for a variety of purposes involving resistance to apoptosis or resistance to stress.
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patent: WO 99/15677 (1999-04-01), None
patent: WO 01/23592 (2001-04-01), None
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Lu, A. & Miller, L. K. The roles of eighte
Blissard Gary
Granados Robert R.
Lin Guangyun
Boyce Thompson Institute for Plant Research Inc.
Brown & Michaels PC
Guzo David
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