Stable aqueous solubilizates of carotenoids and vitamins

Details Stable aqueous solubilizates of carotenoids and vitamins Stable aqueous solubilizates of carotenoids and vitamins

1997-03-10

1999-04-06

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514168, 514474, 514725, A61K 3107, A61K 3134, A61K 31355, A61K 31595

Patent

active

058919074

ABSTRACT:
Stable aqueous solubilizates are disclosed suitable for parenteral administration, of carotenoids and vitamins or vitamin derivatives, in which the carotenoid and the water-insoluble vitamins are, with the aid of a nonionic emulsifier, in the form of a micellar solution, the micelles being smaller than 100 nm, wherein the solubilizates comprise, in amounts based on the solubilizate, at least one carotenoid in a concentration of from 0.1 to 10% by weight, the water-insoluble, lipophilic vitamins or vitamin derivatives in a concentration of from 0.1 to 20% by weight and the nonionic emulsifiers in a concentration of from 1 to 40% by weight, with the proviso that the content of lipophilic vitamins is at least as large as that of the carotenoid.

REFERENCES:
patent: 5453447 (1995-09-01), End et al.

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