Stable aqueous drug suspensions and methods for preparation ther

Details Stable aqueous drug suspensions and methods for preparation ther Stable aqueous drug suspensions and methods for preparation ther

1994-10-25

1997-03-25

Michl, Paul R.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424491, 424494, A61K 914

Patent

active

056142226

ABSTRACT:
Finely divided drug particles are coated with a lipid or bioadhesive polymer to form microspheres having a particle size of about 550 micrometers or less, and coated with two or more enteric coatings, at least one of which is water insoluble, to form microcapsules. The resultant microcapsules can be suspended in an aqueous solution to form stable oral doses of the drug.

REFERENCES:
patent: 4166800 (1979-09-01), Fong
patent: 4818542 (1989-04-01), DeLuca et al.
patent: 5288502 (1994-02-01), McGinity et al.

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