Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1987-04-20
1990-10-16
Teskin, Robin L.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 88, 424 92, 424 95, 514 2, 514 8, 530322, 530370, 530395, 530413, 530414, A61K 3905, A61K 3936, A61K 3902
Patent
active
049633562
ABSTRACT:
A storage-stable, high potency allergenic extract is prepared by ultrafiltration, retaining fractions having molecular weights of from 1000 to 100,000, and drying the retained fraction to a moisture content of less than one weight percent. The extract can also be pretreated with amylase before ultrafiltration, treated with affinity chromatography before drying, and/or treated with gamma radiation after drying.
REFERENCES:
patent: 2908614 (1959-10-01), Muggleton
patent: 4350686 (1982-09-01), Relyveld et al.
patent: 4387091 (1983-06-01), Vijay et al.
Mosbach, Methods Enzymol, vol. XLIV, 1976, pp. 784-790.
Bor, C. Chem. Abst., vol. 96(16) No. 129761k, "Gamma Radiation Sterilization of Pharmaceutical Active Ingredients, Adjuvants and Packaging Materials".
Beigler Myron A.
Calenoff Emanuel
Friesen Gerald L.
Nichols James L.
Goldman Philip M.
Kirn Walter N.
Minnesota Mining and Manufacturing Company
Sell Donald M.
Teskin Robin L.
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