Stable analogs of peptide and polypeptide therapeutics

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Glucagon; related peptides

Reexamination Certificate

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Details

C514S002600, C514S012200, C530S324000

Reexamination Certificate

active

10847220

ABSTRACT:
The present invention relates to compositions of peptide and polypeptide analogs that are resistant to proteolysis, pharmaceutical uses thereof, and methods of preparation thereof.

REFERENCES:
patent: 5118666 (1992-06-01), Habener
patent: 5120712 (1992-06-01), Habener
patent: 5276137 (1994-01-01), Ojima et al.
patent: 5545618 (1996-08-01), Buckley et al.
patent: 5614492 (1997-03-01), Habener
patent: 5766620 (1998-06-01), Heiber et al.
patent: 5958909 (1999-09-01), Habener
patent: 5994500 (1999-11-01), Drucker et al.
patent: 6184201 (2001-02-01), Drucker et al.
patent: 6268343 (2001-07-01), Knudsen et al.
patent: 6277819 (2001-08-01), Efendic
patent: 6358924 (2002-03-01), Hoffmann
patent: 6489295 (2002-12-01), Drucker et al.
patent: 2001/0011071 (2001-08-01), Knudsen et al.
patent: 2004/0242853 (2004-12-01), Greig et al.
patent: WO99/40788 (1999-08-01), None
patent: WO99/43705 (1999-09-01), None
patent: WO99/43706 (1999-09-01), None
patent: WO99/43707 (1999-09-01), None
patent: WO 00/07617 (2000-02-01), None
patent: WO 01/98331 (2001-12-01), None
patent: WO 02/22151 (2002-03-01), None
patent: WO 02/46227 (2002-06-01), None
patent: WO 02/47716 (2002-06-01), None
patent: WO 02/069994 (2002-09-01), None
patent: WO 03/002136 (2003-01-01), None
patent: WO 03/018516 (2003-03-01), None
Mentlein et al., “Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36) amide, peptide histidine methionine and is responsible for their degradation in human serum,”European Journal of Biochemistry, 214(3):829-835 (1993).
Deacon et al., “Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity,”Diabetologia, 41(3):271-278 (1998).
Guarita, et al., “PYY Regulates Pancreatic Exocrine Secretion Through Multiple Receptors in the Awake Rat,” Digestive Diseases and Sciences, 2000, vol. 45(9) 1696-1702.
Keire, et al., “Structure and receptor binding of PYY analogs,” Peptides 23 (2002) 305-321.
Mentlein, Rolf, “Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides,” Regulatory Peptides 85 (1999) 9-24.
Naslund, et al., “Glucagon-like peptide-1 analogue LY315902: Effect on intestinal motility and release of insulin and somatostatin,” Regulatory Peptides 106 (2002) 89-95.

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