Stable amorphous celecoxib composite and process therefor

Details Stable amorphous celecoxib composite and process therefor Stable amorphous celecoxib composite and process therefor

2005-03-08

2005-03-08

Richter, Johann (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

06864373

ABSTRACT:
A process is provided for preparing a celecoxib-crystallization inhibitor composite wherein at least a detectable amount of celecoxib is in amorphous form. Also provided are compositions prepared according to such a process. Also provided is a method of treating a medical condition or disorder in a subject where treatment with a cyclooxygenase-2 inhibitor is indicated, comprising administering, for example orally, a composition of the invention in a therapeutically effective amount.

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Lieberman et al., (1989), Pharmaceutical Dosage Forms: Tablets, vol. 1, pp. 34-36.
The Merck Index, 12thEdition, Therapeutic Category and Biological Activity Index, ed. S. Budavari (1996), pp. Ther-2 to Ther-3 and Ther-12.

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