Stabilizing formulation for preserving the integrity of proteins

Chemistry: analytical and immunological testing – Including sample preparation – Stabilizing or preserving

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436 8, 436 18, 436 86, 252380, 2524081, G01N 100

Patent

active

059982160

ABSTRACT:
The present invention provides stabilizing formulations for maintaining and preserving the integrity of proteins and polypeptides present in a body fluid sample obtained ex-vivo and to be evaluated as a test specimen for either clinical, therapeutic, or research purposes. The stabilizing formulations may be prepared alternatively either as a dry, anhydrous mixture of powders or as an aqueous based liquid containing the dissolved ingredients in admixture. The invention also provides minimalist stabilizing formulations as well as fortified stabilizing formulations which meet specific uses and applications and may be advantageously employed over a wide variety of different time, temperature, and severity of conditions.

REFERENCES:
patent: 4919889 (1990-04-01), Jones et al.
patent: 5240843 (1993-08-01), Gibson et al.
patent: 5474892 (1995-12-01), Jakob et al.
patent: 5541116 (1996-07-01), Bergmann
patent: 5547873 (1996-08-01), Magneson et al.

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