Stabilizing blood cells with aromatic polyaldehyde for use in he

Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Particle count or volume standard or control

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424 3, 436 16, G01N 3100

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active

046983120

ABSTRACT:
Blood cells such as erythrocytes of animal origin are treated with a solution containing water, an organic cosolvent (such as dimethylsulfoxide, alone or admixed with a polyol), an aromatic polyaldehyde (such as phthaldialdehyde) and optionally salts and buffers. In an illustrative case, the treating solution is hypertonic and shrinks goat erythrocytes to the size of human platelets.

REFERENCES:
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patent: 3714345 (1973-01-01), Hirata
patent: 3715427 (1973-02-01), Hirata
patent: 4287087 (1981-09-01), Brinkhous et al.
patent: 4390632 (1983-06-01), Carter

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