Stabilized Trinder reagent

Details Stabilized Trinder reagent Stabilized Trinder reagent

1990-08-30

1992-04-28

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

435 10, 435 11, 435 14, 435 25, 435 28, 514270, 514312, 514376, 514404, 514566, 514709, 514731, 514732, G01N 3315, C12Q 128, C12Q 162

Patent

active

051087332

ABSTRACT:
Spontaneous aspecific coloration in so-called Trinder reagents which can alter subsequent colorimetric determinations is inhibited by adding compounds of the chelating agent class to the solution. The resultant compositions contain a peroxidase enzyme, a phenylpyrazone derivative, a compound of phenolic or aromatic amine structure and a stabilizer. Preferred stabilizers are ethylenediaminetetraacetic acid (EDTA) and diethylenetriaminepentaacetic acid (DTPA).

REFERENCES:
patent: Re29498 (1977-12-01), Meiattini
patent: 3992158 (1976-11-01), Przybylowicz et al.
patent: 4716110 (1987-12-01), Wada et al.
Putz, G. R. et al., Am. J. Med. Technology 42(10):351-6 (1976).
Ziebig, R. et al., Zentrabl. Pharm. Pharmakother. Laboratoriumsdiagn. 125(4):223-8 (1986).

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