Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood
Patent
1983-06-29
1985-12-03
Lacey, David L.
Chemistry: analytical and immunological testing
Hemoglobin, myoglobin, or occult blood
422 56, 427 2, 435 28, 436904, G01N 3352, G01N 2178
Patent
active
045566402
ABSTRACT:
A test composition, device and method for determining a perioxidatively active substance in a test sample, as well as a method for preparing and using the device, are disclosed. The composition comprises an organic hydroperoxide, a benzidine indicator capable of providing a detectable response in the presence of the organic hydroperoxide and a peroxidatively active substance, and, as a stabilizing agent, an aniline chosen from pheny-1-naphthylamine, N,N-dimethylaniline and mixtures thereof. The device comprises a carrier matrix incorporated with the composition, and the method for using the device comprises contacting a test sample with the device and observing a detectable response therein. A method for preparing the device comprises preparing two or more solutions of the ingredients of the composition, wetting the carrier matrix sequentially therewith and drying the matrix after each wetting.
REFERENCES:
patent: 2981606 (1961-04-01), Keston
patent: 4125372 (1978-11-01), Kawai et al.
patent: 4362697 (1982-12-01), Tabb et al.
patent: 4391905 (1983-07-01), Bauer
Boguslaski Mary G.
Gzybowski Michael
Lacey David L.
Miles Laboratories Inc.
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