Stabilized sulfite-free catecholamine compositions

Details Stabilized sulfite-free catecholamine compositions Stabilized sulfite-free catecholamine compositions

1989-10-23

1991-03-26

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514654, 514970, 514973, 514836, A61K 31135

Patent

active

050029738

ABSTRACT:
Novel catecholamine solutions for physiological uses are provided at a pH in the range of 1.0-5.0, comprising catecholamine, acetylcysteine, chelating agent and buffering agents. The compositions are stabilized from oxidation without the use of sulfites and are preferably administered by inhalation.

REFERENCES:
patent: 2698823 (1951-03-01), Bersworth et al.
patent: 3808317 (1974-04-01), Hecht et al.
patent: 3966905 (1976-06-01), Nite
patent: 4150744 (1979-04-01), Fennimore
patent: 4164570 (1979-08-01), Clough et al.
Lachman-Antioxidants and Chelating, Agents As Stabilizers in Liquid Dosage Forms, Drug Cosmet. Ind. 102(2), 43-45, 146-149, (1968).

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