Chemistry: analytical and immunological testing – Involving immune complex formed in liquid phase
Patent
1995-06-07
1997-06-03
Hutzell, Paula K.
Chemistry: analytical and immunological testing
Involving immune complex formed in liquid phase
436 8, 435 71, 5303885, G01N 33536, C07K 1614
Patent
active
056354061
ABSTRACT:
The present invention is directed to an in vitro aqueous composition comprising a drug, preferably tacrolimus or rapamycin, having enhanced stability. The invention utilizes a binding protein, preferably antibodies to tacrolimus or rapamycin, to stabilize the drug in an aqueous matrix.
Grenier Frank
Holzman Thomas F.
Smith Allan H.
Tsurutani Alan C.
Abbott Laboratories
Hutzell Paula K.
Johnson Nancy A.
Levis John F.
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