Stabilized radiopharmaceutical compositions

Details Stabilized radiopharmaceutical compositions Stabilized radiopharmaceutical compositions

2006-05-30

2006-05-30

Jones, Dameron L. (Department: 1618)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C424S001110, C424S009100

Reexamination Certificate

active

07052672

ABSTRACT:
The present invention relates to stabilized99mTc radiopharmaceutical compositions, which include both a radioprotectant and one or more antimicrobial preservative(s), and hence have an extended lifetime of use. The radioprotectant is ascorbic acid, para-aminobenzoic acid, gentisic acid or a salt thereof with a biocompatible cation, and the antimicrobial preservative is one or more compound from the paraben series of preservatives. The invention is particularly useful for cationic, lipophilic99mTc heart imaging agents such as Myoview™.

REFERENCES:
patent: 3939258 (1976-02-01), Niemann
patent: 4233284 (1980-11-01), Fawzi
patent: 4364920 (1982-12-01), Winchell
patent: 4451451 (1984-05-01), Rimmer
patent: 4781912 (1988-11-01), Zanelli et al.
patent: 5093105 (1992-03-01), Flanagan et al.
patent: 5227152 (1993-07-01), Flanagan et al.
patent: 5420321 (1995-05-01), Edwards
patent: 0508724 (1996-08-01), None
Hensel, et.al. (J Pharm Sci 1995; 84(1): 115-118).

Affiliated with

Also associated with

Rating

Stabilized radiopharmaceutical compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stabilized radiopharmaceutical compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stabilized radiopharmaceutical compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3615981