Stabilized radiographic scanning agents

Details Stabilized radiographic scanning agents Stabilized radiographic scanning agents

1978-03-31

1980-11-11

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

424 9, A61K 2900, A61K 4300

Patent

active

042332842

ABSTRACT:
Stable compositions, useful as technetium-99m-based scintigraphic agents, comprise gentisic acid or a pharmaceutically-acceptable salt or ester thereof in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (.sup.99m TcO.sub.4.sup.-) solution. The compositions are especially useful in combination with a phosphate or phosphonate material which carries the radionuclide to bone, thus providing a skeletal imaging agent.

REFERENCES:
patent: 4062933 (1977-12-01), Wolfangel
patent: 4071613 (1978-01-01), Hunter, Jr.
patent: 4104366 (1978-08-01), Schmidt-Dunker et al.
patent: 4133872 (1979-01-01), Schmidt-Dunker et al.
Fujie et al., Chemical Abstracts, vol. 77, No. 5, Jul. 31, 1972, Abstract #33158a.
Okamoto et al., Chemical Abstracts, vol. 82, No. 16, Apr. 21, 1975, Abstract #103156c.

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