Stabilized PVP-I solutions

Details Stabilized PVP-I solutions Stabilized PVP-I solutions

1991-07-16

1992-06-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424427, 424437, 424 7824, 424667, 424668, 424669, 424670, 424671, 424672, A61K 3174

Patent

active

051261278

ABSTRACT:
Povidone-Iodine (PVP-I) solutions stable according to U.S.P. standards and a method for preparing the same are disclosed. The PVP-I solution includes a microbicidal effective amount of available iodine and an alkalinizing agent in an effective amount to maintain the stability of the solution for a desired shelf-life of the solution when said solution is stored in a substantially nonpermeable container, the solution being non-buffered. In preferred embodiments, the iodophor solution is a microbicidal PVP-I solution for ophthalmic use.

REFERENCES:
patent: 4364929 (1982-12-01), Sasmor et al.
patent: 4401651 (1983-08-01), Knutson
patent: 4526751 (1985-07-01), Gartner
patent: 4976969 (1990-12-01), Plamondon

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