Stabilized preparations for use in nebulizers

Details Stabilized preparations for use in nebulizers Stabilized preparations for use in nebulizers

2005-09-20

2005-09-20

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

C424S046000, C424S426000, C424S434000, C424S435000, C424S489000, C424S490000

Reexamination Certificate

active

06946117

ABSTRACT:
Stabilized dispersions are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The dispersions preferably comprise a stabilized colloidal system which may comprise a fluorochemical component. In particularly preferred embodiments, the stabilized dispersions comprise perforated microstructures dispersed in a fluorochemical suspension medium. As density variations between the suspended particles and suspension medium are minimized and attractive forces between microstructures are attenuated, the disclosed dispersions are particularly resistant to degradation, such as by settling or flocculation. In particularly preferred embodiments, the stabilized dispersions may be administered to the lung of a patient using a nebulizer.

REFERENCES:
patent: 3014844 (1961-12-01), Thiel et al.
patent: 4127622 (1978-11-01), Watanabe et al.
patent: 4161516 (1979-07-01), Bell
patent: 4180593 (1979-12-01), Cohan
patent: 4590206 (1986-05-01), Forrester et al.
patent: 4818542 (1989-04-01), DeLuca et al.
patent: 4904479 (1990-02-01), Illum
patent: 5011678 (1991-04-01), Wang et al.
patent: 5069936 (1991-12-01), Yen
patent: 5118494 (1992-06-01), Schultz et al.
patent: 5126123 (1992-06-01), Johnson
patent: 5145684 (1992-09-01), Liversidge et al.
patent: 5173298 (1992-12-01), Meadows
patent: 5182097 (1993-01-01), Byron et al.
patent: 5190029 (1993-03-01), Byron et al.
patent: 5208226 (1993-05-01), Palmer
patent: 5225183 (1993-07-01), Purewal et al.
patent: 5230884 (1993-07-01), Evans et al.
patent: 5254330 (1993-10-01), Ganderton et al.
patent: 5260306 (1993-11-01), Boardman et al.
patent: 5284656 (1994-02-01), Platz et al.
patent: 5299566 (1994-04-01), Davis et al.
patent: 5308620 (1994-05-01), Yen
patent: 5348730 (1994-09-01), Greenleaf et al.
patent: 5354934 (1994-10-01), Pitt et al.
patent: 5376359 (1994-12-01), Johnson
patent: 5437272 (1995-08-01), Fuhrman
patent: 5470885 (1995-11-01), Fuhrman et al.
patent: 5474759 (1995-12-01), Fassberg et al.
patent: 5490498 (1996-02-01), Faithfull et al.
patent: 5492688 (1996-02-01), Byron et al.
patent: 5506203 (1996-04-01), Backstrom et al.
patent: 5518709 (1996-05-01), Sutton et al.
patent: 5518731 (1996-05-01), Meadows
patent: 5518998 (1996-05-01), Backstrom et al.
patent: 5547656 (1996-08-01), Unger
patent: 5562608 (1996-10-01), Sekins et al.
patent: 5569450 (1996-10-01), Duan et al.
patent: 5580575 (1996-12-01), Unger et al.
patent: 5605673 (1997-02-01), Schutt et al.
patent: 5605674 (1997-02-01), Purewal et al.
patent: 5611344 (1997-03-01), Bernstein et al.
patent: 5612053 (1997-03-01), Baichwal
patent: 5616311 (1997-04-01), Yen
patent: 5635159 (1997-06-01), Fu Lu et al.
patent: 5635161 (1997-06-01), Adjei et al.
patent: 5653961 (1997-08-01), McNally et al.
patent: 5653962 (1997-08-01), Akehurst et al.
patent: 5654007 (1997-08-01), Johnson et al.
patent: 5658549 (1997-08-01), Akehurst et al.
patent: 5667809 (1997-09-01), Trevino et al.
patent: 5674471 (1997-10-01), Akehurst et al.
patent: 5674472 (1997-10-01), Akehurst et al.
patent: 5674473 (1997-10-01), Purewal et al.
patent: 5676929 (1997-10-01), Akehurst et al.
patent: 5681545 (1997-10-01), Purewal et al.
patent: 5683676 (1997-11-01), Akehurst et al.
patent: 5683677 (1997-11-01), Purewal et al.
patent: 5688782 (1997-11-01), Neale et al.
patent: 5690954 (1997-11-01), Illum
patent: 5695743 (1997-12-01), Purewal et al.
patent: 5695744 (1997-12-01), Neale et al.
patent: 5707352 (1998-01-01), Sekins et al.
patent: 5718222 (1998-02-01), Lloyd et al.
patent: 5718921 (1998-02-01), Mathiowitz et al.
patent: 5720940 (1998-02-01), Purewal et al.
patent: 5724957 (1998-03-01), Rubsamen et al.
patent: 5725841 (1998-03-01), Duan et al.
patent: 5725871 (1998-03-01), Illum
patent: 5735263 (1998-04-01), Rubsamen et al.
patent: 5736124 (1998-04-01), Akehurst et al.
patent: 5741478 (1998-04-01), Osborne et al.
patent: 5741522 (1998-04-01), Violante et al.
patent: 5743250 (1998-04-01), Gonda et al.
patent: 5743252 (1998-04-01), Rubsamen et al.
patent: 5744123 (1998-04-01), Akehurst et al.
patent: 5744166 (1998-04-01), Illum
patent: 5747445 (1998-05-01), Backstrom et al.
patent: 5755218 (1998-05-01), Johansson et al.
patent: 5756104 (1998-05-01), de Haan et al.
patent: 5766573 (1998-06-01), Purewal et al.
patent: 5770187 (1998-06-01), Hasebe et al.
patent: 5770222 (1998-06-01), Unger et al.
patent: 5770559 (1998-06-01), Manning et al.
patent: 5770585 (1998-06-01), Kaufman et al.
patent: 5804212 (1998-09-01), Illum
patent: 5811406 (1998-09-01), Szoka, Jr. et al.
patent: 5814607 (1998-09-01), Patton
patent: 5817293 (1998-10-01), Akehurst et al.
patent: 5820883 (1998-10-01), Tice et al.
patent: 5830430 (1998-11-01), Unger et al.
patent: 5830853 (1998-11-01), Backstrom et al.
patent: 5855913 (1999-01-01), Hanes et al.
patent: 5856367 (1999-01-01), Barrows et al.
patent: 5858784 (1999-01-01), Debs et al.
patent: 5863554 (1999-01-01), Illum
patent: 5874063 (1999-02-01), Briggner et al.
patent: 5874064 (1999-02-01), Edwards et al.
patent: 5891844 (1999-04-01), Hafner
patent: 5898028 (1999-04-01), Jensen et al.
patent: 5955448 (1999-09-01), Colaco et al.
patent: 5985309 (1999-11-01), Edwards et al.
patent: 6041777 (2000-03-01), Faithfull et al.
patent: 6136295 (2000-10-01), Edwards et al.
patent: RE37053 (2001-02-01), Hanes et al.
patent: 6290991 (2001-09-01), Roser et al.
patent: 6309623 (2001-10-01), Weers et al.
patent: 6433040 (2002-08-01), Dellamary et al.
patent: 6503480 (2003-01-01), Edwards et al.
patent: 6630169 (2003-10-01), Bot et al.
patent: 6652837 (2003-11-01), Edwards et al.
patent: 2036844 (1991-08-01), None
patent: 2136704 (1995-05-01), None
patent: 0 072 046 (1983-02-01), None
patent: 0 274 431 (1988-07-01), None
patent: 0274431 (1988-07-01), None
patent: 0 433 679 (1991-06-01), None
patent: 0372777 (1993-01-01), None
patent: 0391896 (1994-03-01), None
patent: 0536204 (1994-04-01), None
patent: 0611567 (1994-08-01), None
patent: 0 611 567 (1994-08-01), None
patent: 0553298 (1994-11-01), None
patent: 0653205 (1995-05-01), None
patent: 0655237 (1995-05-01), None
patent: 0656206 (1995-06-01), None
patent: 0658101 (1995-06-01), None
patent: 0513127 (1995-07-01), None
patent: 0 663 840 (1995-07-01), None
patent: 0493437 (1995-08-01), None
patent: 0556256 (1995-08-01), None
patent: 0616525 (1995-09-01), None
patent: 0499344 (1995-10-01), None
patent: 0 681 843 (1995-11-01), None
patent: 0587790 (1996-01-01), None
patent: 0605578 (1996-01-01), None
patent: 0588897 (1996-02-01), None
patent: 0 743 860 (1996-11-01), None
patent: 0536235 (1997-01-01), None
patent: 0 773 781 (1997-05-01), None
patent: 0539522 (1998-12-01), None
patent: 0 904 056 (1999-03-01), None
patent: 1 265 615 (1972-03-01), None
patent: 2 105 189 (1983-03-01), None
patent: 02084401 (1990-03-01), None
patent: 03264537 (1991-11-01), None
patent: 89/08449 (1989-09-01), None
patent: 90/13285 (1990-11-01), None
patent: 9104011 (1991-04-01), None
patent: 9111173 (1991-08-01), None
patent: 9112823 (1991-09-01), None
patent: 91/16882 (1991-11-01), None
patent: 9200107 (1992-01-01), None
patent: WO 9211050 (1992-07-01), None
patent: 9211050 (1992-07-01), None
patent: 9214444 (1992-09-01), None
patent: 9218164 (1992-10-01), None
patent: WO 9300951 (1993-01-01), None
patent: 93/00951 (1993-01-01), None
patent: 9311744 (1993-06-01), None
patent: 9311745 (1993-06-01), None
patent: 9314172 (1993-07-01), None
patent: 94/07514 (1994-04-01), None
patent: 9408627 (1994-04-01), None
patent: 9500128 (1995-01-01), None
patent: 95/01324 (1995-01-01), None
patent: 9505194 (1995-02-01), None
patent: 9515118 (1995-06-01), None
patent: 9517195 (1995-06-01), None
patent: 9523613 (1995-09-01), None
patent: 9524892 (1995-09-01), None
patent: 9527476 (1995-10-01), None
patent: 9531182 (1995-11-01), None
patent: 9531964 (1995-11-01), None
patent: 96/03116 (1996-02-01), None
patent: 9609814 (1996-04-01), None
patent: 9615814 (1996-05-01), None
patent: 9618388 (1996-06-01), None
patent: 9619197 (1996-06-01), None
patent: 9619198 (1996-06-01), None
patent: 9619199 (1996-06-01), None
patent: 9619968 (1996-07-01), None
patent: 9626746 (1996-09-01), None
p

Affiliated with

Also associated with

Rating

Stabilized preparations for use in nebulizers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stabilized preparations for use in nebulizers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stabilized preparations for use in nebulizers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3437936