Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-05-19
1999-11-30
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A61K 3133
Patent
active
059943386
ABSTRACT:
A stabilized pharmaceutical composition having a combined quinupristine/dalfopristine base and containing an at least stoichiometric amount of methanesulphonic acid or hydrochloric acid and being characterized in that its pH ranges from about 3.5 to about 5. Methods of making and using the stabilized composition are also disclosed.
REFERENCES:
patent: 4590004 (1986-05-01), Corbet et al.
patent: 4798827 (1989-01-01), Barriere et al.
"Pharmacokinetics and Suction Blister Fluid Penetration of a Semisynthetic Injectable Streptogramin RP 59500 (RP 57669/RP 54476)," European Journal of Clinical Microbiology & Infectious Diseases, vol. 13, No. 9 (Sep. 1994).
International Search Report for PCT/FR97/02047 (Mailed Mar. 11, 1998).
Bounine Jean-Paul
Conrath Guillaume
Henley III Raymond
Rhone Poulenc Rorer S.A.
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