Stabilized pharmaceutical compositions containing derivatives of

Details Stabilized pharmaceutical compositions containing derivatives of Stabilized pharmaceutical compositions containing derivatives of

1993-09-13

1996-10-15

Prior, Kimberly J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

514168, A61K 3159

Patent

active

055654428

ABSTRACT:
The invention relates to a process for stabilizing pharmaceutically active derivatives of vitamin D2 and D3. At least one pharmaceutically active vitamin D derivative is dissolved in a solvent with an antioxidant. This solution is mixed with a pharmaceutically acceptable stabilizer and at least one solid pharmaceutical excipient or carrier which is present in an amount sufficient to impart the characteristics of a solid to the composition. Finally, the solvent is removed.

REFERENCES:
patent: 3932634 (1976-01-01), Kardys
patent: 4729895 (1988-03-01), Makino et al.
patent: 4929610 (1990-05-01), Meier et al.
Fiedler, Dr. Herbert P. "Dictionary for Pharmaceutical, Cosmetical and Associated Fields", 3rd, Revised and Supplemented Edition. 1989.

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